The Far-West saga
In 1850s, in a probable reality of South America, we get acquainted with Twilight (Twi) and her brothers Jo and Elroy.
They have a precious blue bull in their possession, coveted by Ogrean, the kingpin of the town. Hopefully for them, Ogrean is arrested (temporarily) by Ted Marshall, the sheriff for his possible trafficking.
Notably, Ogrean is possibly involved in some of the crystal skulls discoveries, during his travel to New Honduras.
Twi who was dancing in the saloon of Madame Butterbutt, the town’s hallucinogenic toads-to-lick dispenser (insert some other romantic subplots involving the other dancer etc.) decides to go traveling in a freakus (freak show/circus).
She is now close to the West Coast, where she hopes to succeed in her writing and other artistic skills.